产品货号：
Z17550
中文名称：
GSTA4抗体
英文名称：
Anti-GSTA4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GSTA4 Antibody |
| 指标别名 | Glutathione S transferase A4;Glutathione S transferase A4 4;GST class alpha member 4;GSTA4;GSTA4 4;GTA4 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | GSTA4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human GSTA4 recombinant protein (Position:E29-P222). |
| 实际分子量 | 26KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Glutathione S-transferase A4,also known as GSTA4,is an enzyme which in humans is encoded by the GSTA4 gene.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families.These enzymes function in the detoxification of electrophilic compounds,including carcinogens,therapeutic drugs,environmental toxins and products of oxidative stress,by conjugation with glutathione.The genes encoding these enzymes are known to be highly polymorphic.These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs.At present,eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified:alpha,kappa,mu,omega,pi,sigma,theta and zeta.This gene encodes a glutathione S-transferase belonging to the alpha class.The alpha class genes,located in a cluster mapped to chromosome 6,are the most abundantly expressed glutathione S-transferases in liver (hepatocytes) and kidney (proximal tubules).In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver,the alpha class of these enzymes exhibit glutathione peroxidase activity,thereby protecting the cells from reactive oxygen species and the products of peroxidation. |
| Uniprot ID | O15217 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | glutathione S-transferase alpha 4 |
| 蛋白名全称 | Glutathione S-transferase A4 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section IHC 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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